Fecal Calprotectin as a Predictor of COVID-19 Severity

Abstract Coronavirus disease 2019 (COVID-19) is highly transmittable through contact with respiratory droplets. The virus also shed in fecal matter. Some patients may present effects more than one system; however, there are no defined biomarkers that can accurately predict the course or progression of disease. study aimed to estimate severity disease, correlate biochemical predictors, identify valuable indicative gastrointestinal and determine cutoff values. A cross-sectional was conducted on COVID-19 admitted Kafrelsheikh University Hospital (isolation unit) between July 10, 2020, October 30, 2020. diagnosis confirmed via reverse transcription-polymerase chain reaction (RT-PCR), which employed for detection viral RNA. We conclude lymphopenia, elevated C-reactive protein (CRP) level, liver enzymes were among most important laboratory findings patients. Statistically significant differences platelet count, neutrophil D-dimer calprotectin levels observed presenting chest symptoms only both (p = 0.004; < 0.001; 0.010; 0.003; 0.001, respectively). protein, D-dimer, positively correlated severity. value involvement 165.0, a sensitivity 88.1% specificity 76.5%.